Holyoke, Massachusetts is located Western Massachusetts in the Connecticut River Valley. Bordered by West Springfield on the south; Westfield, Southampton, and Easthampton on the west; and separated from South Hadley and Chicopee by the Connecticut River on the east. Holyoke is 90 miles west of Boston; 34 miles north of Hartford, Connecticut; and 142 miles from New York City. Principal highways are U.S. Route 5 and Interstate Route 91 going N-S, and the Massachusetts Turnpike (Interstate Route 90) running E-W. Interchange No. 4 is located almost on the southern border of Holyoke. Amtrak passenger rail service is available from nearby Springfield. The Pioneer Valley Railroad (PVRR) and the Springfield Terminal Railway (STRR) provide freight service and interchange traffic in Holyoke. The PVRR operates a warehouse and distribution facility in the city. Contact numbers: PVRR (413) 568-3331; STRR (508) 663-1073.

Some information gathered on Holyoke, MA is courtesy of Commonwealth Communities at Mass.gov