Amesbury, Massachusetts is located Northeastern Massachusetts, bordered by Merrimac on the west; South Hampton, New Hampshire, on the north; Salisbury on the east; and Newburyport and West Newbury on the south. Amesbury is located on the Merrimack River 10 miles northeast of Haverhill, 43 miles north of Boston, and 260 miles from New York City. The principal highways serving the area are Interstate 95, which runs from Maine to Florida, and Interstate 495, the Outer Belt around Boston. There is no passenger or freight rail service in Amesbury, but the network of intermodal facilities serving Massachusetts is easily accessible.

Some information gathered on Amesbury, MA is courtesy of Commonwealth Communities at Mass.gov